Publications

  1. Meiri, D. and Breiman, A. (2009). Arabidopsis ROF1 (FKBP62) modulates thermotolerance by interacting with HSP90.1 and affecting the accumulation of HsfA2-regulated sHSPs. Plant J. 59, 387-99

  2. Meiri, D., Greeve, M.A., Brunet, A., Finan, D., Wells, C.D., LaRose, J., and Rottapel, R. (2009). Modulation of Rho guanine exchange factor Lfc activity by protein kinase A-mediated phosphorylation. Mol Cell Biol. 29, 5963-5973.

  3. Meiri, D., Tazat, K., Cohen-Peer, R., Farchi-Pisanty, O., Aviezer-Hagai, K., Avni, A., and Breiman, A. (2010). Involvement of Arabidopsis ROF2 (FKBP65) in thermotolerance. Plant Mol Biol 72, 191-203.

  4. Cohen-Peer R, Schuster S, Meiri D, Breiman A., and Avni A. (2010). Sumoylation of Arabidopsis heat shock factor A2 (HsfA2) modifies its activity during acquired thermotholerance. Plant Mol Biol 74, 33-45.

  5. Meiri D., Marshall CB., Greeve, M.A., Bakal C., Kim B., Suarez F., LaRose J., Fine N.,  Ikura, M.,  and Rottapel R. (2011). Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein dependent RhoGEF inhibition. Mol Cell 45, 642-55.

  6. Marshall, C.B., Meiri, D., Smith, M.J., Mazhab-Jafari, M.T., Gasmi-Seabrook, G.M., Rottapel R., Stambolic, V., and Ikura, M. (2012). Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts. Methods. 57, 473-85.

  7. Lighezan L., Meiri, D., Breiman A., Neagu A. (2013) Circular dichroism and the secondary structure of the ROF2 protein from Arabidopsis thaliana. J Biol Phys. 39(4):635-48.

  8. Cullis J*., Meiri, D*., Radulovich N., LaRose J., Medrano M., Marcotte R., Marshall C.B.,  Moffat J., Neel B., Gingras AC., Robert Rottapel (2014) The RhoGEF GEF-H1 is required for RAS oncogene-driven pancreatic cancer. Cancer cell 25(2):181-95.
    *These authors contributed equally to the work.

  9. Meiri D., Marshall CB., LaRose J., Gingras AC., Ikura M., Robert Rottapel. (2014) Mechanistic insight into the GPCR-mediated activation of the microtubule-associated RhoA-specific guanine exchange factor, GEF-H1. Nature Communications 11(5):4857.

  10. Mokady D., Meiri D. (2014) RhoGTPases- a novel link between cytoskeleton organization and cisplatin resistance. Drug Resistance Updates (impact factor 9.96).